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  • Assessment of frontal EEG measurement in out-of-hospital cardiac arrest: a prospective observational feasibility study – study protocol

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Assessment of frontal EEG measurement in out-of-hospital cardiac arrest: a prospective observational feasibility study – study protocol
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  • Published on: 28 April 2025
    Pre- and in-hospital pre-ROSC EEG during cardiopulmonary resucitation

    February 23, 2025, Eichinger et al. published a plan for pre-hospital bispectral index measurements (BIS) during CPR in out-of-hospital cardiac arrest patients and at hospitalization to
    a) determine feasibility of BIS during CPR,
    b) assess neurological outcomes -particularly return of consciousness before ROSC and
    c) grade cerebral performance category (CPC) at 1 month

    Highlighted strenghts were systematic data collection and focus on feasibility of BIS during and after CPR, whereas limitations included recruiting 45 patients, reliance on a particular EMS system and prioritization study feasibility over clinical outcomes (1).

    However, there are more weaknesses:
    Muscle signals (EMG) and artifacts in BIS due heart massage are expected to blur the EEG assessments – but easily eliminated by sedatives and paralytic agents. The major problem is 'noise' from EEG devices, electrical installations and human activities at the scene of arrest because the 'noise level' dictates whether electrocortical activities can be identified (2).
    Quality of Life (QoL) interviews of family members are suggested although one's own
    perception of life quality before CPR does not relate to qualities one month later.
    The reference list includes 18 articles of which 17 were published in 2017 or later and one neurosurgical from 1975.
    The number of patients is 45 whivch weakens the upper 95% confidence interval for th...

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    Conflict of Interest:
    None declared.