Associations between maternal adversity and offspring CV measures
| Pooled | Boys | Girls | ||
| Outcome | Exposure | Fold change (95% CI) | Fold change (95% CI) | Fold change (95% CI) |
| Resting heart rate (bpm) | Perceived impact score | 0.999 (0.998 to 1.001) | 1.000 (0.997 to 1.002) | 0.999 (0.997 to 1.001) |
| Adversity no | 0.997 (0.992 to 1.003) | 0.998 (0.990 to 1.005) | 0.996 (0.989 to 1.004) | |
| Systolic blood pressure (mm Hg) | Perceived impact score | 1.000 (0.999 to 1.001) | 1.000 (0.998 to 1.002) | 1.000 (0.998 to 1.001) |
| Adversity no | 0.998 (0.994 to 1.001) | 0.998 (0.993 to 1.003) | 0.998 (0.993 to 1.002) | |
| Diastolic blood pressure (mm Hg) | Perceived impact sficore | 1.000 (0.999 to 1.002) | 0.999 (0.997 to 1.002) | 1.001 (0.999 to 1.003) |
| Adversity no | 0.999 (0.994 to 1.003) | 0.996 (0.989 to 1.002) | 1.001 (0.996 to 1.007) | |
| Pulse-wave velocity | Perceived impact score | 0.999 (0.997 to 1.001) | 0.999 (0.997 to 1.001) | 1.001 (0.998 to 1.004) |
| Adversity no | 0.998 (0.991 to 1.005) | 0.9928 (0.982 to 1.004) | 1.001 (0.992 to 1.010) | |
| Carotid Intima Media Thickness | Perceived impact score | 1.000 (0.998 to 1.002) | 1.001 (0.998 to 1.004) | 1.000 (0.997 to 1.002) |
| Adversity no | 1.001 (0.996 to 1.007) | 1.001 (0.993 to 1.010) | 1.001 (0.994 to 1.008) |
Models adjusted for child age, alcohol use in pregnancy; tobacco use in pregnancy; ethnic group; parity; age at delivery and maternal education.
Fold changes corresponds to a four unit change in adversity measures.
NB, pulse wave velocity and carotid Intima media thickness were only measured at one time point (17 years of age).
CV, cardiovascular.