Table 4

Correlations change in ALT and changes in metabolic parameters

Variable	Full CCI cohort n=262				CCI cohort with abnormal baseline ALT levels n=153†
Variable	Unadjusted r	P value*	Adjusted r	P value*	Unadjusted r	P value*	Adjusted r	P value*
Δ Body weight (%)	0.191	0.043	0.198	0.004	0.253	0.056	0.278	0.003
Δ Fasting glucose (mg/dL)	0.124	0.118	0.176	0.004	0.184	0.051	0.305	1.2×10^–4
Δ HbA1c (%)	0.176	0.043	0.148	0.033	0.220	0.018	0.253	0.005
Δ Triglycerides (mg/dL)	0.032	0.741	0.025	0.490	0.091	0.428	0.106	0.163
Δ Cholesterol (mg/dL)	−0.076	0.375	−0.031	0.563	−0.046	0.663	−0.020	0.605
Δ HDL cholesterol (mg/dL)	−0.115	0.160	−0.069	0.219	−0.145	0.182	−0.118	0.207
Δ LDL cholesterol (mg/dL)	−0.049	0.526	−0.022	0.476	−0.042	0.669	−0.032	0.690

ΔMeans change from baseline.
*Unadjusted and adjusted Pearson’s correlations. Adjustments while controlling for individual baseline covariate levels, age, sex, race (African-American vs other), diabetes duration, body mass index and insulin use.
†ALT levels >19 in women and >30 in men.
ALT, alanine aminotransferase; CCI, continuous care intervention; HbA1c, glycosylated haemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein.