Table 5

Association between recruitment rate (number of patients/centre/month) and trial characteristics

Characteristic	n	Median	IQR	p Value
Setting
Hospital	82	1.22	0.58–2.61
General practice	20	0.52	0.23–0.85
Mixed	25	0.98	0.46–3.57
Community	16	1.62	0.38–4	0.043*†
Other	8	3.62	0.53–11.48
Arms
2	101	0.98	0.44–3.01
3	30	0.89	0.39–5.86
4	13	1.04	0.76–2.45
>4	7	0.61	0.39–2.43	0.889†
Control type
Placebo	30	1.29	0.54–4.01
Active	121	0.88	0.42–2.6	0.427‡
Original target recruitment
≤200	14	0.49	0.21–2.23
201–400	40	1.30	0.51–2.26
401–600	31	0.87	0.42–2.33	0.033§
601–800	15	0.87	0.39–2.61
>800	50	1.34	0.58–5.73
Final target recruitment
≤200	17	0.87	0.59–3.5
201–400	49	1.96	0.72–5.68
401–600	27	0.72	0.42–1.67
601–800	13	0.41	0.07–1.14	<0.001§
>800	45	0.89	0.39–4.42
Total recruitment
≤200	24	0.60	0.34–1.72
201–400	48	1.40	0.42–4.28	<0.001§
401–600	28	0.84	0.39–1.61
601–800	12	1.51	0.28–2.17
>800	39	1.38	0.43–5.48
Timing of final follow-up
<1 month	9	1.77	0.39–7.48
1–6 months	41	1.11	0.73–5.43	0.352§
6–18 months	63	0.62	0.31–1.98
>18 months	33	0.87	0.42–3.85